2qjk Summary

pdbe.org/2qjk
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Crystal Structure Analysis of mutant rhodobacter sphaeroides bc1 with stigmatellin and antimycin

The structure was published by Esser, L., Elberry, M., Zhou, F., Yu, C.A., Yu, L., and Xia, D., in 2008 in a paper entitled "Inhibitor-complexed structures of the cytochrome bc1 from the photosynthetic bacterium Rhodobacter sphaeroides." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 3.1 Å and deposited in 2007.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 3 biomacromolecules, namely Cytochrome b, Cytochrome c1, and Ubiquinol-cytochrome c reductase iron-sulfur subunit.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Cytochrome b Q02761 (3-430) (CYB_RHOSH)search Rhodobacter sphaeroidessearch 96% 428 100%
D Cytochrome b Q02761 (3-430) (CYB_RHOSH)search Rhodobacter sphaeroidessearch 96% 428 100%
G Cytochrome b Q02761 (3-430) (CYB_RHOSH)search Rhodobacter sphaeroidessearch 96% 428 100%
J Cytochrome b Q02761 (3-430) (CYB_RHOSH)search Rhodobacter sphaeroidessearch 96% 428 100%
M Cytochrome b Q02761 (3-430) (CYB_RHOSH)search Rhodobacter sphaeroidessearch 96% 428 100%
P Cytochrome b Q02761 (3-430) (CYB_RHOSH)search Rhodobacter sphaeroidessearch 96% 428 100%
B Cytochrome c1 Q02760 (23-278) (CY1_RHOSH)search Rhodobacter sphaeroidessearch 97% 256 100%
E Cytochrome c1 Q02760 (23-278) (CY1_RHOSH)search Rhodobacter sphaeroidessearch 97% 256 100%
H Cytochrome c1 Q02760 (23-278) (CY1_RHOSH)search Rhodobacter sphaeroidessearch 97% 256 100%
K Cytochrome c1 Q02760 (23-278) (CY1_RHOSH)search Rhodobacter sphaeroidessearch 97% 256 100%
N Cytochrome c1 Q02760 (23-278) (CY1_RHOSH)search Rhodobacter sphaeroidessearch 97% 256 100%
Q Cytochrome c1 Q02760 (23-278) (CY1_RHOSH)search Rhodobacter sphaeroidessearch 97% 256 100%
C Ubiquinol-cytochrome c reductase iron-sulfur subunit Q02762 (9-187) (UCRI_RHOSH)search Rhodobacter sphaeroidessearch 96% 179 100%
F Ubiquinol-cytochrome c reductase iron-sulfur subunit Q02762 (9-187) (UCRI_RHOSH)search Rhodobacter sphaeroidessearch 96% 179 100%
I Ubiquinol-cytochrome c reductase iron-sulfur subunit Q02762 (9-187) (UCRI_RHOSH)search Rhodobacter sphaeroidessearch 96% 179 100%
L Ubiquinol-cytochrome c reductase iron-sulfur subunit Q02762 (9-187) (UCRI_RHOSH)search Rhodobacter sphaeroidessearch 96% 179 100%
O Ubiquinol-cytochrome c reductase iron-sulfur subunit Q02762 (9-187) (UCRI_RHOSH)search Rhodobacter sphaeroidessearch 96% 179 100%
R Ubiquinol-cytochrome c reductase iron-sulfur subunit Q02762 (9-187) (UCRI_RHOSH)search Rhodobacter sphaeroidessearch 96% 179 100%


This entry contains 3 unique UniProt proteins:

UniProt accession Name Organism PDB
Q02761 (3 - 430) Cytochrome b Rhodobacter sphaeroides
Q02760 (23 - 278) Cytochrome c1 Rhodobacter sphaeroides
Q02762 (9 - 187) Ubiquinol-cytochrome c reductase iron-sulfur subunit Rhodobacter sphaeroides

Chain Structural classification (CATH) Sequence family (Pfam)
A, D, G, J, M, P (Q02761) Cytochrome Bc1 Complex; Chain Csearch PF00032: Cytochrome b(C-terminal)/b6/petDsearch, PF13631: Cytochrome b(N-terminal)/b6/petBsearch
B, E, H, K, N, Q (Q02760) Cytochrome csearch, Single alpha-helices involved in coiled-coils or other helix-helix interfacessearch PF02167: Cytochrome C1 familysearch
C, F, I, L, O, R (Q02762) Single helix binsearch, 'Rieske'-like iron-sulphur domainssearch PF00355: Rieske [2Fe-2S] domainsearch, PF10399: Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signalsearch

Chain ID Cellular component (GO) Biological process (GO) Molecular function (GO)
A, D, G, J, M, P (Q02761) membranesearch plasma membranesearch respiratory chainsearch integral component of membranesearch oxidation-reduction processsearch respiratory electron transport chainsearch metal ion bindingsearch electron carrier activitysearch oxidoreductase activitysearch
B, E, H, K, N, Q (Q02760) integral component of membranesearch plasma membranesearch respiratory chainsearch membranesearch oxidation-reduction processsearch iron ion bindingsearch electron carrier activitysearch heme bindingsearch metal ion bindingsearch
C, F, I, L, O, R (Q02762) membranesearch integral component of membranesearch plasma membranesearch oxidation-reduction processsearch hydrogen ion transmembrane transportsearch ubiquinol-cytochrome-c reductase activitysearch 2 iron, 2 sulfur cluster bindingsearch oxidoreductase activitysearch iron-sulfur cluster bindingsearch metal ion bindingsearch oxidoreductase activity, acting on diphenols and related substances as donorssearch

Chain InterPro annotation
A, D, G, J, M, P Cytochrome b/b6, N-terminalsearch Cytochrome b/b6, C-terminalsearch Di-haem cytochrome, transmembranesearch Cytochrome b/b6-like domainsearch
B, E, H, K, N, Q Cytochrome c1search Cytochrome c-like domainsearch
C, F, I, L, O, R Rieske iron-sulphur protein, C-terminalsearch Ubiquinol-cytochrome c reductase, iron-sulphur subunitsearch Rieske iron-sulphur proteinsearch Rieske [2Fe-2S] iron-sulphur domainsearch Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signalsearch Twin-arginine translocation pathway, signal sequence, bacterial/archaealsearch