Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Complexed with a Chloro-Indazole Compound
The structure was published by Nettles, K.W., Bruning, J.B., Gil, G., et al., Kim, Y., Joachmiak, A., and Greene, G.L., in 2008 in a paper entitled "NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.39 Å and deposited in 2007.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely Estrogen receptor and Nuclear receptor coactivator 2.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms heterotetramers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: