Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Complexed to an Ether Estradiol Compound
The structure was published by Nettles, K.W., Bruning, J.B., Gil, G., et al., Kim, Y., Joachmiak, A., and Greene, G.L., in 2008 in a paper entitled "NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.15 Å and deposited in 2007.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely Estrogen receptor and Nuclear receptor coactivator 2.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms heterotetramers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: