2qc9 Summary


Mouse Notch 1 Ankyrin Repeat Intracellular Domain

The structure was published by Coleman, M.L., McDonough, M.A., Hewitson, K.S., et al., Oldham, N.J., Ratcliffe, P.J., and Schofield, C.J., in 2007 in a paper entitled "Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.35 Å and deposited in 2007.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Notch 1 protein.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Notch 1 protein Q01705 (1899-2106) (NOTC1_MOUSE)search Mus musculussearch < 90% 210 93%
B Notch 1 protein Q01705 (1899-2106) (NOTC1_MOUSE)search Mus musculussearch < 90% 210 93%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q01705 (1899 - 2106) Notch 1 protein Mus musculus

Chain Structural classification (CATH) Sequence family (Pfam)
A, B Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeatsearch Ankyrin repeatsearch, Ankyrin repeats (3 copies)search
Chain InterPro annotation
A, B Ankyrin repeatsearch Ankyrin repeat-containing domainsearch