2q9s Summary


Linoleic Acid Bound to Fatty Acid Binding Protein 4

The structure was published by Gillilan, R.E., Ayers, S.D., and Noy, N., in 2007 in a paper entitled "Structural Basis for Activation of Fatty Acid-binding Protein 4." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 2007.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Fatty acid-binding protein. This molecule has the UniProt identifier P04117 (FABP4_MOUSE)search. The sample contained 155 residues which is 100% of the natural sequence. Out of 155 residues 130 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Fatty acid-binding protein P04117 (1-132) (FABP4_MOUSE)search Mus musculussearch 98% 155 84%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P04117 (1 - 132) Fatty acid-binding protein Mus musculus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P04117) Fatty acid binding protein-likesearch Lipocalinsearch PF00061: Lipocalin / cytosolic fatty-acid binding protein familysearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A (P04117) transportsearch white fat cell differentiationsearch cholesterol homeostasissearch cytokine productionsearch brown fat cell differentiationsearch cellular response to lithium ionsearch positive regulation of inflammatory responsesearch negative regulation of transcription, DNA-templatedsearch negative regulation of protein kinase activitysearch lipid bindingsearch transporter activitysearch cytoplasmsearch nucleoplasmsearch nucleussearch

Chain InterPro annotation
A Cytosolic fatty-acid bindingsearch Lipocalin/cytosolic fatty-acid binding domainsearch Calycin-likesearch Calycinsearch