2q60 Summary

pdbe.org/2q60
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Crystal structure of the ligand binding domain of polyandrocarpa misakiensis rxr in tetramer in absence of ligand

The structure was published by Borel, F., de Groot, A., Juillan-Binard, C., et al., Pebay-Peyroula, E., Fontecilla-Camps, J.C., and Ferrer, J.L., in 2008 in a paper entitled "Crystal structure of the ligand-binding domain of the retinoid X receptor from the ascidian polyandrocarpa misakiensis." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.9 Å and deposited in 2007.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Retinoid X receptor.

The molecule most likely forms homotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Retinoid X receptor Q9UAF1 (103-337) (Q9UAF1_POLMI)search Polyandrocarpa misakiensissearch < 90% 258 78%
B Retinoid X receptor Q9UAF1 (103-337) (Q9UAF1_POLMI)search Polyandrocarpa misakiensissearch < 90% 258 78%
C Retinoid X receptor Q9UAF1 (103-337) (Q9UAF1_POLMI)search Polyandrocarpa misakiensissearch < 90% 258 78%
D Retinoid X receptor Q9UAF1 (103-337) (Q9UAF1_POLMI)search Polyandrocarpa misakiensissearch < 90% 258 78%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q9UAF1 (103 - 337) Retinoid X receptor Polyandrocarpa misakiensis

Chain Structural classification (CATH) Sequence family (Pfam)
A, B, C, D Retinoid X Receptorsearch Ligand-binding domain of nuclear hormone receptorsearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A, B, C, D (Q9UAF1) regulation of transcription, DNA-templatedsearch steroid hormone mediated signaling pathwaysearch steroid hormone receptor activitysearch sequence-specific DNA binding transcription factor activitysearch zinc ion bindingsearch DNA bindingsearch nucleussearch

Chain InterPro annotation
A, B, C, D Retinoid X receptor/HNF4search Nuclear hormone receptor, ligand-binding, coresearch Steroid hormone receptorsearch Nuclear hormone receptor, ligand-bindingsearch