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Crystal structure of the ligand binding domain of polyandrocarpa misakiensis rxr in tetramer in absence of ligand

X-ray diffraction
2.9Å resolution
PDB entry 2q60 coloured by chain, front view.
PDB entry 2q60 coloured by chain, side view.
PDB entry 2q60 coloured by chain, top view.
Source organism: Polyandrocarpa misakiensis
Assembly composition:
homo tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Retinoid X receptor
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Multimeric state: homo tetramer
Accessible surface area: 36040.78 Å2
Buried surface area: 7008.84 Å2
Dissociation area: 3,504.42 Å2
Dissociation energy (ΔGdiss): -4.22 kcal/mol
Dissociation entropy (TΔSdiss): 38.95 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-193640

Macromolecules

Retinoid X receptor
Chains: A, B, C, D
Length: 258 amino acids
Theoretical weight: 29.07 KDa
Source organism: Polyandrocarpa misakiensis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UAF1 (Residues: 103-337; Coverage: 65%)
Gene name: PmRXR
Pfam: Ligand-binding domain of nuclear hormone receptor
InterPro:
CATH: Retinoid X Receptor
Retinoid X receptor in PDB entry 2q60, assembly 1, front view.
Retinoid X receptor in PDB entry 2q60, assembly 1, side view.
Retinoid X receptor in PDB entry 2q60, assembly 1, top view.
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