› 2q3x

X-ray diffraction
1.73Å resolution

The RIM1alpha C2B domain

Released:
DOI: 10.2210/pdb2q3x/pdb
PDB entry 2q3x coloured by chain, front view.
PDB entry 2q3x coloured by chain, side view.
PDB entry 2q3x coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Crystal structure of the RIM1alpha C2B domain at 1.7 A resolution.
Guan R, Dai H, Tomchick DR, Dulubova I, Machius M, S��dhof TC, Rizo J
Biochemistry 46 8988-98 (2007)
PMID: 17630786

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191614 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Regulating synaptic membrane exocytosis protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 171 amino acids
Theoretical weight: 18.96 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9JIR4 (Residues: 1447-1615; Coverage: 11%)
Gene names: Rim1, Rims1
Sequence domains: C2 domain
Structure domains: C2 domain

Ligands and Environments

3 bound ligands:
Ligand SO4 7 x SO4
Ligand CL 3 x CL
Ligand NA 1 x NA
1 modified residue:
Ligand MSE 10 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: P3121
Unit cell:
a: 62.037Å b: 62.037Å c: 145.18Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.179 0.178 0.215
Expression system: Escherichia coli BL21

Quick links

Citations

3 review citations

Synaptic vesicle fusion.
Rizo et al. (2008)
2 more

4 mentions without citation

RIM C2B Domains Target Presynaptic Active Zone Functions to PIP2-Containing Membranes.
de Jong et al. (2018)
3 more