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EBI PDBe PDBeView

PDBe Entry: 2q3e view

Structure of human UDP-glucose dehydrogenase complexed with NADH and UDP-glucose
Summary
Header Oxidoreductasesearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.0 Å, R-factor: 17.343%, Free R-factor: 20.521%, Spacegroup: P 1 21 1
Released 03/07/2007, deposition: 30/05/2007, last revision: 10/11/2009
Authors Kavanagh, K.L.search; Guo, K.search; Bunkoczi, G.search; Savitsky, P.search; Pilka, E.search; Bhatia, C.search; Smee, C.search; Berridge, G.search; Von Delft, F.search; Wiegelt, J.search; Arrowsmith, C.search; Sundstrom, M.search; Edwards, A.search; Oppermann, U.search; Structural Genomics Consortium (SGC)search
Primary citation Structure of human UDP-glucose dehydrogenase complexed with NADH and UDP-glucose
TO BE PUBLISHED
Keywords UDP-GLUCOSE 6-DEHYDROGENASEsearch, hexamersearch, Structural Genomicssearch, Structural Genomics Consortiumsearch, SGCsearch, Oxidoreductasesearch
EC 1.1.1.22 ExPASy BRENDA search (A B C D E F G H I J K L)
Organism Homo sapiens(human) 9606search(A B C D E F G H I J K L)
UniProt UDP-glucose 6-dehydrogenase (EC 1.1.1.22) (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) O60701search (A B C D E F G H I J K L)
Solvent A, B, C, D, E, F, G, H, I, J, K, L
Polymers
Id Name Type UniProt Residues Observed
A, B, C, D, E, F, G, H, I, J, K, L UDP-glucose 6-dehydrogenase Protein O60701 (UGDH_HUMAN)search
 467 98%
Heterogens
Id Name Ligands
A, G, I, F, C, D, L, K, B, H, E, J CHLORIDE ION CL search
A, B, C, D, E, F, G, H, I, J, K, L NICOTINAMIDE-ADENINE-DINUCLEOTIDE NAD search
A, B, C, D, E, F, G, H, I, J, K, L URIDINE-5'-DIPHOSPHATE-GLUCOSE UPG search
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