2pxy

X-ray diffraction
2.23Å resolution

Crystal structures of immune receptor complexes

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-106903 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
Ig-like domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 114 amino acids
Theoretical weight: 12.54 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5R1F5 (Residues: 19-112; Coverage: 100%)
Gene name: TRAV6D-7
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins
Ig-like domain-containing protein Chain: B
Molecule details ›
Chain: B
Length: 111 amino acids
Theoretical weight: 12.08 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: A2NTY6 (Residues: 32-144; Coverage: 98%)
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins
H-2 class II histocompatibility antigen, A-U alpha chain Chain: C
Molecule details ›
Chain: C
Length: 183 amino acids
Theoretical weight: 20.77 KDa
Source organism: Mus musculus
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: P14438 (Residues: 1-178; Coverage: 78%)
Gene name: H2-Aa
Sequence domains:
Structure domains:
H-2 class II histocompatibility antigen, A-U beta chain Chain: D
Molecule details ›
Chain: D
Length: 189 amino acids
Theoretical weight: 22.57 KDa
Source organism: Mus musculus
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: P06344 (Residues: 29-217; Coverage: 80%)
Sequence domains:
Structure domains:
Myelin basic protein (MBP)-peptide Chain: P
Molecule details ›
Chain: P
Length: 13 amino acids
Theoretical weight: 1.43 KDa

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P4122
Unit cell:
a: 97.603Å b: 97.603Å c: 175.561Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.218 0.218 0.253
Expression systems:
  • Escherichia coli
  • Drosophila melanogaster