2puy Summary


Crystal Structure of the BHC80 PHD finger

The structure was published by Lan, F., Collins, R.E., De Cegli, R., et al., Gozani, O., Cheng, X., and Shi, Y., in 2007 in a paper entitled "Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.43 Å and deposited in 2007.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely PHD finger protein 21A and Histone H3.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A PHD finger protein 21A Q96BD5 (486-543) (PF21A_HUMAN)search Homo sapienssearch < 90% 60 100%
B PHD finger protein 21A Q96BD5 (486-543) (PF21A_HUMAN)search Homo sapienssearch < 90% 60 100%
E Histone H3 Not available
Synthetic Not available 10 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q96BD5 (486 - 543) PHD finger protein 21A Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A, B Zinc/RING finger domain, C3HC4 (zinc finger)search PHD-fingersearch

Chain ID Molecular function (GO)
A, B (Q96BD5) zinc ion bindingsearch

Chain InterPro annotation
A, B Zinc finger, RING-typesearch Zinc finger, PHD-typesearch Zinc finger, FYVE/PHD-typesearch Zinc finger, RING/FYVE/PHD-typesearch Zinc finger, PHD-type, conserved sitesearch Zinc finger, PHD-fingersearch