PPARgamma Ligand binding domain complexed with a farglitazar analogue gw4709
The structure was published by Trump, R.P., Cobb, J.E., Shearer, B.G., et al., Pearce, K.H., Billin, A.N., and Hoekstra, W.J., in 2007 in a paper entitled "Cocrystal structure guided array synthesis of PPARgamma inverse agonists" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 2007.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Peroxisome proliferator-activated receptor gamma.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms homodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: