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EBI PDBe PDBeView

PDBe Entry: 2pnx view

The PHD finger of ING4 in complex with an H3K4Me3 histone peptide
Summary
Header GENE REGULATIONsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 1.8 Å, R-factor: 19.9%, Free R-factor: 21.1%, Spacegroup: P 43
Released 15/04/2008, deposition: 25/04/2007, last revision: 22/09/2009
Authors Champagne, K.S.search; Johnson, K.search; Kutateladze, T.G.search
Primary citation ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation
MOL.CELLsearch vol:33, pag:248-256 (2009) [PubMed ID 19187765 ]search
Keywords protein-peptide complexsearch, chromatinsearch, zinc fingersearch, histonesearch, GENE REGULATIONsearch
Organism Homo sapiens(human) 9606search(A C)
UniProt Inhibitor of growth protein 4 (p29ING4) Q9UNL4search (A C)
Solvent A, B, C, D
Polymers
Id Name Type UniProt Residues Observed
A, C Inhibitor of growth protein 4 Protein Q9UNL4 (ING4_HUMAN)search
 55 92%
B, D H3K4Me3 peptide Protein
12 91%
Heterogens
Id Name Ligands
A, C ZINC ION ZN search
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