2plc Summary

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PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C FROM LISTERIA MONOCYTOGENES

The structure was published by Moser, J., Gerstel, B., Meyer, J.E., Chakraborty, T., Wehland, J., and Heinz, D.W., in 1997 in a paper entitled "Crystal structure of the phosphatidylinositol-specific phospholipase C from the human pathogen Listeria monocytogenes." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 1997.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C. This molecule has the UniProt identifier P34024 (PLC_LISMO)search. The sample contained 274 residues which is 93% of the natural sequence. Out of 274 residues 273 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C P34024 (43-316) (PLC_LISMO)search Listeria monocytogenes EGD-esearch 93% 274 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P34024 (43 - 316) PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C Listeria monocytogenes

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P34024) Bacterial PLCsearch Phosphatidylinositol (PI) phosphodiesterasesearch PF00388: Phosphatidylinositol-specific phospholipase C, X domainsearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A (P34024) lipid metabolic processsearch pathogenesissearch lipid catabolic processsearch phosphoric diester hydrolase activitysearch lyase activitysearch phosphatidylinositol diacylglycerol-lyase activitysearch extracellular regionsearch cytoplasmsearch

Chain InterPro annotation
A Phospholipase C, phosphatidylinositol-specific , X domainsearch PLC-like phosphodiesterase, TIM beta/alpha-barrel domainsearch