2pfm Summary


Crystal Structure of Adenylosuccinate Lyase (PurB) from Bacillus anthracis

A publication describing this structure is not available. The depositing authors are Levdikov, V.M.search; Blagova, E.V.search; Baumgart, M.search; Moroz, O.V.search; Wilkinson, A.J.search; Wilson, K.S.search

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2007.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Adenylosuccinate lyase.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Adenylosuccinate lyase Q81ZH6 (1-435) (Q81ZH6_BACAN)search Bacillus anthracissearch 100% 444 97%
B Adenylosuccinate lyase Q81ZH6 (1-435) (Q81ZH6_BACAN)search Bacillus anthracissearch 100% 444 97%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q81ZH6 (1 - 435) Adenylosuccinate lyase Bacillus anthracis

Chain Structural classification (CATH) Sequence family (Pfam)
A, B (Q81ZH6) Fumarase/aspartase (N-terminal domain)search, Fumarase/aspartase (Central domain)search, Fumarase/aspartase (C-terminal domain)search PF00206: Lyasesearch, PF10397: Adenylosuccinate lyase C-terminussearch

Chain ID Molecular function (GO) Biological process (GO)
A, B (Q81ZH6) catalytic activitysearch (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activitysearch N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activitysearch lyase activitysearch purine ribonucleotide biosynthetic processsearch

Chain InterPro annotation
A, B Fumarate lyase familysearch Adenylosuccinate lyasesearch L-Aspartase-likesearch Adenylosuccinate lyase C-terminalsearch Fumarate lyase, conserved sitesearch Fumarate lyase, N-terminalsearch Fumarase/histidase, N-terminalsearch