Crystal structure of human PPAR-gamma-ligand binding domain complexed with an indole-based modulator
The structure was published by Einstein, M., Akiyama, T.E., Castriota, G.A., et al., Meinke, P.T., Wood, H.B., and Berger, J.P., in 2008 in a paper entitled "The differential interactions of peroxisome proliferator-activated receptor gamma ligands with Tyr473 is a physical basis for their unique biological activities." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.25 Å and deposited in 2007.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Peroxisome proliferator-activated receptor gamma.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms homodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: