2ovy

X-ray diffraction
1.8Å resolution

Crystal structure of the catalytic domain of rat phosphodiesterase 10A

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo trimer
PDBe Complex ID:
PDB-CPX-193052 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Chain: A
Molecule details ›
Chain: A
Length: 362 amino acids
Theoretical weight: 41.66 KDa
Source organism: Rattus norvegicus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9QYJ6 (Residues: 452-794; Coverage: 43%)
Gene name: Pde10a
Sequence domains: 3'5'-cyclic nucleotide phosphodiesterase
Structure domains: 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: R3
Unit cell:
a: 120.797Å b: 120.797Å c: 83.495Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.16 0.157 0.198
Expression system: Spodoptera frugiperda