Assemblies
Assembly Name:
Cathepsin S
Multimeric state:
monomeric
Accessible surface area:
9805.38 Å2
Buried surface area:
1081.0 Å2
Dissociation area:
244.39
Å2
Dissociation energy (ΔGdiss):
-2.16
kcal/mol
Dissociation entropy (TΔSdiss):
4.24
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-150575
Assembly Name:
Cathepsin S
Multimeric state:
monomeric
Accessible surface area:
9697.73 Å2
Buried surface area:
465.36 Å2
Dissociation area:
232.68
Å2
Dissociation energy (ΔGdiss):
-4.54
kcal/mol
Dissociation entropy (TΔSdiss):
3.74
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-150575
Assembly Name:
Cathepsin S
Multimeric state:
homo tetramer
Accessible surface area:
34683.12 Å2
Buried surface area:
7415.82 Å2
Dissociation area:
2,241
Å2
Dissociation energy (ΔGdiss):
8.79
kcal/mol
Dissociation entropy (TΔSdiss):
40.46
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-150577
Assembly Name:
Cathepsin S
Multimeric state:
homo dimer
Accessible surface area:
19212.27 Å2
Buried surface area:
2560.49 Å2
Dissociation area:
270.54
Å2
Dissociation energy (ΔGdiss):
18.33
kcal/mol
Dissociation entropy (TΔSdiss):
14
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-150576
Macromolecules
Chains: A, B
Length: 220 amino acids
Theoretical weight: 24.39 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Pfam: Papain family cysteine protease
InterPro:
SCOP: Papain-like
Length: 220 amino acids
Theoretical weight: 24.39 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P25774 (Residues: 112-331; Coverage: 70%)
Pfam: Papain family cysteine protease
InterPro:
- Papain-like cysteine peptidase superfamily
- Peptidase C1A, papain C-terminal
- Papain-like cysteine endopeptidase
- Peptidase C1A
- Cysteine peptidase, cysteine active site
- Cysteine peptidase, histidine active site
- Cysteine peptidase, asparagine active site
SCOP: Papain-like
