2ooq Summary


Crystal Structure of the Human Receptor Phosphatase PTPRT

The structure was published by Barr, A.J., Ugochukwu, E., Lee, W.H., et al., Burgess-Brown, N.A., Muller, S., and Knapp, S., in 2009 in a paper entitled "Large-scale structural analysis of the classical human protein tyrosine phosphatome." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 2007.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Receptor-type tyrosine-protein phosphatase T.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Receptor-type tyrosine-protein phosphatase T O14522 (868-1151) (PTPRT_HUMAN)search Homo sapienssearch < 90% 286 98%
B Receptor-type tyrosine-protein phosphatase T O14522 (868-1151) (PTPRT_HUMAN)search Homo sapienssearch < 90% 286 98%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
O14522 (868 - 1151) Receptor-type tyrosine-protein phosphatase T Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A, B Protein tyrosine phosphatase superfamilysearch Protein-tyrosine phosphatasesearch

Chain ID Molecular function (GO) Biological process (GO)
A, B (O14522) phosphatase activitysearch protein tyrosine phosphatase activitysearch protein dephosphorylationsearch dephosphorylationsearch

Chain InterPro annotation
A, B Protein-tyrosine phosphatase, receptor/non-receptor typesearch Protein-tyrosine/Dual specificity phosphatasesearch Protein-tyrosine phosphatase, active sitesearch Protein-tyrosine phosphatase-likesearch