2olv Summary


Structural Insight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Donor Ligand Complex

The structure was published by Lovering, A.L., de Castro, L.H., Lim, D., and Strynadka, N.C., in 2007 in a paper entitled "Structural insight into the transglycosylation step of bacterial cell-wall biosynthesis." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.8 Å and deposited in 2007.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Penicillin-binding protein 2.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Penicillin-binding protein 2 Q9R744 (60-727) (Q9R744_STAAU)search Staphylococcus aureussearch 92% 669 92%
B Penicillin-binding protein 2 Q9R744 (60-727) (Q9R744_STAAU)search Staphylococcus aureussearch 92% 669 92%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q9R744 (60 - 727) Penicillin-binding protein 2 Staphylococcus aureus

Chain Structural classification (SCOP) Sequence family (Pfam)
A, B PBP transglycosylase domain-likesearch, beta-Lactamase/D-ala carboxypeptidasesearch Penicillin binding protein transpeptidase domainsearch, Transglycosylasesearch

Chain ID Cellular component (GO) Molecular function (GO)
A, B (Q9R744) membranesearch penicillin bindingsearch

Chain InterPro annotation
A, B Glycosyl transferase, family 51search Penicillin-binding protein, transpeptidasesearch Beta-lactamase/transpeptidase-likesearch Lysozyme-like domainsearch