2oj2 Summary


PDB entry 2oj2 (supersedes 2a4y)

NMR Structure Analysis of the Hematopoetic Cell Kinase SH3 Domain complexed with an artificial high affinity ligand (PD1)

The structure was published by Schmidt, H., Hoffmann, S., Tran, T., et al., Stangler, T., Wiesehan, K., and Willbold, D., in 2007 in a paper entitled "Solution Structure of a Hck SH3 Domain Ligand Complex Reveals Novel Interaction Modes" (abstract).

The structure was determined using NMR spectroscopy and deposited in 2007.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Hematopoetic Cell Kinase, SH3 domain and artificial peptide PD1.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Hematopoetic Cell Kinase, SH3 domain P08631 (61-141) (HCK_HUMAN)search Homo sapienssearch < 90% 86 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P08631 (61 - 141) Hematopoetic Cell Kinase, SH3 domain Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A SH3 Domainssearch SH3 domainsearch
Chain InterPro annotation
A SH3 domainsearch