› 2oh8

X-ray diffraction
1.8Å resolution

Myoglobin cavity mutant I28W

Released:
DOI: 10.2210/pdb2oh8/pdb
PDB entry 2oh8 coloured by chain, front view.
PDB entry 2oh8 coloured by chain, side view.
PDB entry 2oh8 coloured by chain, top view.
Source organism: Physeter catodon
Primary publication:
Ligand pathways in myoglobin: a review of Trp cavity mutations.
Olson JS, Soman J, Phillips GN
IUBMB Life 59 552-62
PMID: 17701550

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135409 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myoglobin Chain: A
Molecule details ›
Chain: A
Length: 154 amino acids
Theoretical weight: 17.44 KDa
Source organism: Physeter catodon
Expression system: Escherichia coli
UniProt:
  • Canonical: P02185 (Residues: 1-154; Coverage: 100%)
Gene name: MB
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

2 bound ligands:
Ligand SO4 2 x SO4
Ligand HEM 1 x HEM
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P6
Unit cell:
a: 91.438Å b: 91.438Å c: 45.9Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.156 0.156 0.18
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Development of recombinant hemoglobin-based oxygen carriers.
Varnado et al. (2013)
6 more

2 mentions without citation

Identification of Druggable Kinase Target Conformations Using Markov Model Metastable States Analysis of apo-Abl.
Paul et al. (2020)
1 more