crystal structure of aminoquinazoline 36 bound to Lck
The structure was published by DiMauro, E.F., Newcomb, J., Nunes, J.J., et al., Zhao, H., Zhu, L., and Zhu, X., in 2006 in a paper entitled "Discovery of Aminoquinazolines as Potent, Orally Bioavailable Inhibitors of Lck: Synthesis, SAR, and in Vivo Anti-Inflammatory Activity" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 2007.
The experimental data on which the structure is based was not deposited.
This PDB entry contains multiple copies of the structure of Proto-oncogene tyrosine-protein kinase LCK.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: