Human estrogen receptor alpha ligand-binding domain in complex with estradiol and the E2#23 FN3 monobody
The structure was published by Koide, A., Abbatiello, S., Rothgery, L., and Koide, S., in 2002 in a paper entitled "Probing protein conformational changes in living cells by using designer binding proteins: application to the estrogen receptor." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.95 Å and deposited in 2006.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely Estrogen receptor and Fibronectin.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms heterotetramers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: