2o9s Summary


The second SH3 domain from ponsin

The structure was published by Gehmlich, K., Pinotsis, N., Hayess, K., et al., El Banayosy, A., Wilmanns, M., and Ehler, E., in 2007 in a paper entitled "Paxillin and ponsin interact in nascent costameres of muscle cells" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 0.83 Å and deposited in 2006.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Ponsin. This molecule has the UniProt identifier Q9BX66 (SRBS1_HUMAN)search. The sample contained 67 residues which is < 90% of the natural sequence. Out of 67 residues 67 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Ponsin Q9BX66 (870-930) (SRBS1_HUMAN)search Homo sapienssearch < 90% 67 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q9BX66 (870 - 930) Ponsin Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A SH3 Domainssearch Variant SH3 domainsearch

Chain ID Biological process (GO)
A (Q9BX66) actin filament organizationsearch insulin receptor signaling pathwaysearch

Chain InterPro annotation
A SH3 domainsearch c-Cbl associated proteinsearch