Crystal Structure of the Human Pregnane X Receptor LBD in complex with an SRC-1 coactivator peptide and T0901317
The structure was published by Xue, Y., Chao, E., Zuercher, W.J., Willson, T.M., Collins, J.L., and Redinbo, M.R., in 2007 in a paper entitled "Crystal structure of the PXR-T1317 complex provides a scaffold to examine the potential for receptor antagonism." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.8 Å and deposited in 2006.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely Orphan nuclear receptor PXR and Nuclear Receptor Coactivator 1 isoform 3.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: