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EBI PDBe PDBeView

PDBe Entry: 2nw8 view

Crystal Structure of Tryptophan 2,3-dioxygenase (TDO) from Xanthomonas campestris in complex with ferrous heme and tryptophan. Northeast Structural Genomics Target XcR13.
Summary
Header OXIDOREDUCTASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 1.6 Å, R-factor: 17.1%, Free R-factor: 18.9%, Spacegroup: P 31 2 1
Released 19/12/2006, deposition: 14/11/2006, last revision: 24/02/2009
Authors Forouhar, F.search; Anderson, J.L.R.search; Mowat, C.G.search; Bruckmann, C.search; Thackray, S.J.search; Seetharaman, J.search; Ho, C.K.search; Ma, L.C.search; Cunningham, K.search; Janjua, H.search; Zhao, L.search; Xiao, R.search; Liu, J.search; Baran, M.C.search; Acton, T.B.search; Rost, B.search; Montelione, G.T.search; Champman, S.K.search; Tong, L.search; Northeast Structural Genomics Consortium (NESG)search
Primary citation Molecular insights into substrate recognition and catalysis by tryptophan 2,3-dioxygenase.
PROC.NATL.ACAD.SCI.USAsearch vol:104, pag:473-478 (2007) [PubMed ID 17197414 ]search
Keywords all alpha-helical proteinsearch, Structural Genomicssearch, PSI-2search, Protein Structure Initiativesearch, Northeast Structural Genomics Consortiumsearch, NESGsearch, OXIDOREDUCTASEsearch
EC 1.13.11.11 ExPASy BRENDA search (A B)
Organism Xanthomonas campestris pv. campestris 340search(A B)
UniProt Tryptophan 2,3-dioxygenase Q8PDA8search (A B)
Solvent A, B
Related entries 1yw0, 2nw7, 2nw9, 1zee, 2nwb
Polymers
Id Name Type UniProt Residues Observed
A, B Tryptophan 2,3-dioxygenase Protein Q8PDA8 (T23O_XANCP)search
 306 86%
Heterogens
Id Name Ligands
B MANGANESE (II) ION MN search
A, B TRYPTOPHAN TRP search
A, B PROTOPORPHYRIN IX CONTAINING FE HEM search
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