2nqb Summary

pdbe.org/2nqb
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Drosophila Nucleosome Structure

A publication describing this structure is not available. The depositing authors are Luger, K.search; Chakravarthy, S.search

This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 2006.

The experimental data on which the structure is based was also deposited.

This entry contains 20 copies of 5 unique biopolymers (complete list).

The molecule most likely forms heterodecamers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Histone H3 P02299 (2-136) (H3_DROME)search Drosophila melanogastersearch 99% 135 72%
E Histone H3 P02299 (2-136) (H3_DROME)search Drosophila melanogastersearch 99% 135 72%
B Histone H4 P84040 (2-103) (H4_DROME)search Drosophila melanogastersearch 99% 103 83%
F Histone H4 P84040 (2-103) (H4_DROME)search Drosophila melanogastersearch 99% 103 83%
C Histone H2A P84051 (2-124) (H2A_DROME)search Drosophila melanogastersearch 97% 123 86%
G Histone H2A P84051 (2-124) (H2A_DROME)search Drosophila melanogastersearch 97% 123 86%
D Histone H2B P02283 (2-123) (H2B_DROME)search Drosophila melanogastersearch 99% 123 77%
H Histone H2B P02283 (2-123) (H2B_DROME)search Drosophila melanogastersearch 99% 123 77%


This entry contains 4 unique UniProt proteins:

UniProt accession Name Organism PDB
P02299 (2 - 136) Histone H3 Drosophila melanogaster
P84040 (2 - 103) Histone H4 Drosophila melanogaster
P84051 (2 - 124) Histone H2A Drosophila melanogaster
P02283 (2 - 123) Histone H2B Drosophila melanogaster

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, E (P02299) Nucleosome core histonessearch Histone, subunit Asearch PF00125: Core histone H2A/H2B/H3/H4search
B, F (P84040) Nucleosome core histonessearch Histone, subunit Asearch PF00125: Core histone H2A/H2B/H3/H4search
C, G (P84051) Histone, subunit Asearch PF00125: Core histone H2A/H2B/H3/H4search
D, H (P02283) Histone, subunit Asearch PF00125: Core histone H2A/H2B/H3/H4search

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A, E (P02299) DNA bindingsearch protein heterodimerization activitysearch protein bindingsearch nucleosomesearch nucleussearch chromosomesearch
B, F (P84040) protein heterodimerization activitysearch DNA bindingsearch protein bindingsearch nucleosomesearch nucleussearch chromosomesearch lipid particlesearch nucleosome assemblysearch centrosome duplicationsearch
C, G (P84051) DNA bindingsearch protein heterodimerization activitysearch nucleosomesearch nucleussearch chromosomesearch lipid particlesearch nucleosome assemblysearch centrosome duplicationsearch
D, H (P02283) protein heterodimerization activitysearch DNA bindingsearch protein bindingsearch nucleussearch lipid particlesearch chromosomesearch nucleosomesearch NuA4 histone acetyltransferase complexsearch nucleosome assemblysearch

Chain InterPro annotation
A, E Histone H3/CENP-Asearch Histone coresearch Histone-foldsearch
B, F Histone H4search Histone coresearch Histone-foldsearch Histone H4, conserved sitesearch
C, G Histone H2Asearch Histone coresearch Histone-foldsearch
D, H Histone H2Bsearch Histone coresearch Histone-foldsearch