2nmt Summary



The structure was published by Bhatnagar, R.S., Futterer, K., Farazi, T.A., et al., Gokel, G.W., Gordon, J.I., and Waksman, G., in 1998 in a paper entitled "Structure of N-myristoyltransferase with bound myristoylCoA and peptide substrate analogs." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.9 Å and deposited in 1998.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of MYRISTOYL-COA\:PROTEIN N-MYRISTOYLTRANSFERASE. This molecule has the UniProt identifier P14743 (NMT_YEAST)search. The sample contained 422 residues which is 93% of the natural sequence. Out of 422 residues 413 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A MYRISTOYL-COA\:PROTEIN N-MYRISTOYLTRANSFERASE P14743 (34-455) (NMT_YEAST)search Saccharomyces cerevisiae S288csearch 93% 422 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P14743 (34 - 455) MYRISTOYL-COA\:PROTEIN N-MYRISTOYLTRANSFERASE Saccharomyces cerevisiae

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P14743) N-myristoyl transferase, NMTsearch Aminopeptidasesearch PF01233: Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domainsearch, PF02799: Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domainsearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A (P14743) glycylpeptide N-tetradecanoyltransferase activitysearch transferase activity, transferring acyl groupssearch transferase activitysearch cytoplasmsearch cytosolsearch N-terminal protein myristoylationsearch N-terminal peptidyl-glycine N-myristoylationsearch replicative cell agingsearch

Chain InterPro annotation
A Myristoyl-CoA:protein N-myristoyltransferasesearch Acyl-CoA N-acyltransferasesearch Myristoyl-CoA:protein N-myristoyltransferase, N-terminalsearch Myristoyl-CoA:protein N-myristoyltransferase, C-terminalsearch Myristoyl-CoA:protein N-myristoyltransferase, conserved sitesearch