2myo Summary



The structure was published by Yang, Y., Nanduri, S., Sen, S., and Qin, J., in 1998 in a paper entitled "The structural basis of ankyrin-like repeat function as revealed by the solution structure of myotrophin." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1998.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of MYOTROPHIN. This molecule has the UniProt identifier P62775 (MTPN_RAT)search. The sample contained 118 residues which is 100% of the natural sequence. Out of 118 residues 118 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A MYOTROPHIN P62775 (1-118) (MTPN_RAT)search Rattus norvegicussearch 100% 118 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P62775 (1 - 118) MYOTROPHIN Rattus norvegicus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P62775) Ankyrin repeatsearch Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeatsearch PF12796: Ankyrin repeats (3 copies)search

Chain ID Biological process (GO) Cellular component (GO) Molecular function (GO)
A (P62775) regulation of barbed-end actin filament cappingsearch positive regulation of cell growthsearch positive regulation of protein metabolic processsearch positive regulation of cardiac muscle hypertrophysearch cell growthsearch positive regulation of macromolecule biosynthetic processsearch striated muscle cell differentiationsearch catecholamine metabolic processsearch positive regulation of NF-kappaB transcription factor activitysearch cerebellar granule cell differentiationsearch neuron differentiationsearch skeletal muscle tissue regenerationsearch cytosolsearch extracellular exosomesearch axonsearch cytoplasmsearch nucleussearch F-actin capping protein complexsearch perinuclear region of cytoplasmsearch protein bindingsearch

Chain InterPro annotation
A Ankyrin repeatsearch Ankyrin repeat-containing domainsearch