› 2mjx

Solution NMR

Solution NMR structure of a mismatch DNA

Released:
DOI: 10.2210/pdb2mjx/pdb
PDB entry 2mjx coloured by chain, ensemble of 8 models, front view.
PDB entry 2mjx coloured by chain, ensemble of 8 models, side view.
PDB entry 2mjx coloured by chain, ensemble of 8 models, top view.
Source organism: synthetic construct
Primary publication:
Double GC:GC mismatch in dsDNA enhances local dynamics retaining the DNA footprint: a high-resolution NMR study.
Ghosh A, Kar RK, Krishnamoorthy J, Chatterjee S, Bhunia A
ChemMedChem 9 2059-64 (2014)
PMID: 25080019

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115623 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
DNA (5'-D(*GP*CP*GP*CP*AP*TP*GP*CP*TP*AP*CP*GP*CP*G)-3') Chain: A
Molecule details ›
Chain: A
Length: 14 nucleotides
Theoretical weight: 4.28 KDa
Source organism: synthetic construct
Expression system: Not provided
DNA (5'-D(*CP*GP*CP*GP*TP*AP*CP*GP*AP*TP*GP*CP*GP*C)-3') Chain: B
Molecule details ›
Chain: B
Length: 14 nucleotides
Theoretical weight: 4.28 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 36%
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

11 citation in other articles

Self-assembly of a nine-residue amyloid-forming peptide fragment of SARS corona virus E-protein: mechanism of self aggregation and amyloid-inhibition of hIAPP.
Ghosh et al. (2015)
10 more

2 mentions without citation

A survey of recent unusual high-resolution DNA structures provoked by mismatches, repeats and ligand binding.
Satange et al. (2018)
1 more