2mhb Summary

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PDB entry 2mhb (supersedes 1mhb)

THE STRUCTURE OF HORSE METHAEMOGLOBIN AT 2.0 ANGSTROMS RESOLUTION

The structure was published by Ladner, R.C., Heidner, E.J., and Perutz, M.F., in 1977 in a paper entitled "The structure of horse methaemoglobin at 2-0 A resolution." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 1977.

A re-refinement of this structure, using the same experimental data but carried out by different authors, is available as entry 1g0b.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely HEMOGLOBIN (AQUO MET) (ALPHA CHAIN) and HEMOGLOBIN (AQUO MET) (BETA CHAIN).

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A HEMOGLOBIN (AQUO MET) (ALPHA CHAIN) P01958 (2-142) (HBA_HORSE)search Equus caballussearch 99% 141 100%
B HEMOGLOBIN (AQUO MET) (BETA CHAIN) P02062 (1-146) (HBB_HORSE)search Equus caballussearch 100% 146 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P01958 (2 - 142) HEMOGLOBIN (AQUO MET) (ALPHA CHAIN) Equus caballus
P02062 (1 - 146) HEMOGLOBIN (AQUO MET) (BETA CHAIN) Equus caballus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P01958) Globinssearch Globinssearch PF00042: Globinsearch
B (P02062) Globinssearch Globinssearch PF00042: Globinsearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A (P01958) heme bindingsearch iron ion bindingsearch oxygen bindingsearch oxygen transporter activitysearch metal ion bindingsearch oxygen transportsearch transportsearch hemoglobin complexsearch
B (P02062) iron ion bindingsearch heme bindingsearch oxygen bindingsearch oxygen transporter activitysearch metal ion bindingsearch oxygen transportsearch transportsearch hemoglobin complexsearch

Chain InterPro annotation
A Globinsearch Haemoglobin, alphasearch Haemoglobin, pisearch Globin-likesearch Globin, structural domainsearch
B Globinsearch Haemoglobin, betasearch Globin-likesearch Globin, structural domainsearch