› 2m32

Solution NMR

Alpha-1 integrin I-domain in complex with GLOGEN triple helical peptide

Released:
DOI: 10.2210/pdb2m32/pdb
PDB entry 2m32 coloured by chain, ensemble of 10 models, front view.
PDB entry 2m32 coloured by chain, ensemble of 10 models, side view.
PDB entry 2m32 coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
The structure of integrin α1I domain in complex with a collagen-mimetic peptide.
Chin YK, Headey SJ, Mohanty B, Patil R, McEwan PA, Swarbrick JD, Mulhern TD, Emsley J, Simpson JS, Scanlon MJ
J Biol Chem 288 36796-809 (2013)
PMID: 24187131

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157419 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Integrin alpha-1 Chain: A
Molecule details ›
Chain: A
Length: 192 amino acids
Theoretical weight: 21.51 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P56199 (Residues: 168-359; Coverage: 17%)
Gene name: ITGA1
Sequence domains: von Willebrand factor type A domain
Structure domains: von Willebrand factor, type A domain
GLOGEN peptide Chains: B, C, D
Molecule details ›
Chains: B, C, D
Length: 23 amino acids
Theoretical weight: 1.96 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand MG 1 x MG
1 modified residue:
Ligand HYP 18 x HYP

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 67%
Refinement method: simulated annealing
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

1 review citation

Role of prolyl hydroxylation in the molecular interactions of collagens.
Rappu et al. (2019)
4 other articles

7 mentions without citation

The structure of integrin α1I domain in complex with a collagen-mimetic peptide.
Chin et al. (2013)
6 more