› 2lz1

Solution NMR

Solution NMR Structure of the DNA-Binding Domain of Human NF-E2-Related Factor 2, Northeast Structural Genomics Consortium (NESG) Target HR3520O

Released:
DOI: 10.2210/pdb2lz1/pdb
PDB entry 2lz1 coloured by chain, ensemble of 20 models, front view.
PDB entry 2lz1 coloured by chain, ensemble of 20 models, side view.
PDB entry 2lz1 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Eletsky A, Pulavarti SVSRK, Lee D, Kohan E, Janjua H, Xiao R, Acton TB, Everett JK, Montelione GT, Szyperski T, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172457 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nuclear factor erythroid 2-related factor 2 Chain: A
Molecule details ›
Chain: A
Length: 90 amino acids
Theoretical weight: 10.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q16236 (Residues: 445-523; Coverage: 13%)
Gene names: NFE2L2, NRF2
Sequence domains: bZIP Maf transcription factor
Structure domains: Transcription factor, Skn-1-like, DNA-binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 88%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

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