2lll Summary


Solution NMR structure of C-terminal globular domain of human Lamin-B2, Northeast Structural Genomics Consortium target HR8546A

A publication describing this structure is not available. The depositing authors are Lemak, A.search; Yee, A.search; Houliston, S.search; Garcia, M.search; Xu, C.search; Min, J.search; Montelione, G.T.search; Arrowsmith, C.search; Northeast Structural Genomics Consortium (NESG)search; Structural Genomics Consortium (SGC)search; Chaperone-Enabled Studies of Epigenetic Regulation Enzymes (CEBS)search

The structure was determined using NMR spectroscopy and deposited in 2011.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Lamin-B2. This molecule has the UniProt identifier Q03252 (LMNB2_HUMAN)search. The sample contained 139 residues which is < 90% of the natural sequence. Out of 139 residues 121 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Lamin-B2 Q03252 (449-569) (LMNB2_HUMAN)search Homo sapienssearch < 90% 139 87%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q03252 (449 - 569) Lamin-B2 Homo sapiens

Chain Sequence family (Pfam)
A Lamin Tail Domainsearch

Chain ID Cellular component (GO) Molecular function (GO)
A (Q03252) lamin filamentsearch nuclear inner membranesearch intermediate filamentsearch structural molecule activitysearch

Chain InterPro annotation
A Lamin Tail Domainsearch Intermediate filament proteinsearch Laminsearch