EC 3.4.19.12: Ubiquitinyl hydrolase 1
Reaction catalysed:
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Systematic name:
-
Alternative Name(s):
- Ubiquitin C-terminal hydrolase
- Ubiquitin carboxyl-terminal hydrolase
- Ubiquitin thiolesterase
- Yeast ubiquitin hydrolase
GO terms
Biochemical function:
Biological process:
- cellular response to xenobiotic stimulus
- muscle cell development
- neuromuscular process
- positive regulation of glycolytic process
- negative regulation of MAP kinase activity
- proteasome-mediated ubiquitin-dependent protein catabolic process
- eating behavior
- axonal transport of mitochondrion
- protein deubiquitination
- regulation of macroautophagy
- adult walking behavior
- axon target recognition
- axonogenesis
- ubiquitin-dependent protein catabolic process
- proteolysis
- response to ischemia
- male germ cell proliferation
Protein family (Pfam)
InterPro annotations
CATH domain