2lb7 Summary


Hevein-type Antifungal Peptide with a Unique 10-Cysteine Motif

The structure was published by Dubovskii, P.V., Vassilevski, A.A., Slavokhotova, A.A., et al., Grishin, E.V., Egorov, T.A., and Arseniev, A.S., in 2011 in a paper entitled "Solution structure of a defense peptide from wheat with a 10-cysteine motif." (abstract).

The structure was determined using NMR spectroscopy and deposited in 2011.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Antimicrobial peptide 1a. This molecule has the UniProt identifier P85966 (AMP_TRIKH)search. The sample contained 44 residues which is 98% of the natural sequence. Out of 44 residues 44 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Antimicrobial peptide 1a P85966 (1-44) (AMP_TRIKH)search Triticum kiharaesearch 98% 44 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P85966 (1 - 44) Antimicrobial peptide 1a Triticum kiharae

Chain Structural classification (CATH) Sequence family (Pfam)
A (P85966) Wheat Germ Agglutinin (Isolectin 2); domain 1search PF00187: Chitin recognition proteinsearch

Chain ID Biological process (GO) Molecular function (GO)
A (P85966) defense responsesearch killing of cells of other organismsearch defense response to bacteriumsearch defense response to fungussearch chitin bindingsearch

Chain InterPro annotation
A Chitin-binding, type 1search