› 2l5m

Solution NMR

Solution structure of GF-17 in complex with micelles

Released:
DOI: 10.2210/pdb2l5m/pdb
PDB entry 2l5m coloured by chain, ensemble of 20 models, front view.
PDB entry 2l5m coloured by chain, ensemble of 20 models, side view.
PDB entry 2l5m coloured by chain, ensemble of 20 models, top view.
Source organism: synthetic construct
Primary publication:
Decoding the functional roles of cationic side chains of the major antimicrobial region of human cathelicidin LL-37.
Wang G, Epand RF, Mishra B, Lushnikova T, Thomas VC, Bayles KW, Epand RM
Antimicrob Agents Chemother 56 845-56 (2012)
PMID: 22083479

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162865 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GF-17 Chain: A
Molecule details ›
Chain: A
Length: 18 amino acids
Theoretical weight: 2.11 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

10 review citations

Staphylococcus aureus virulence factors in evasion from innate immune defenses in human and animal diseases.
Zecconi et al. (2013)
9 more

5 mentions without citation

High-quality 3D structures shine light on antibacterial, anti-biofilm and antiviral activities of human cathelicidin LL-37 and its fragments.
Wang et al. (2014)
4 more