› 2kx8

Solution NMR

NMR structure of stem-loop 4 from the human 7SK snRNA in complex with arginine

Released:
DOI: 10.2210/pdb2kx8/pdb
PDB entry 2kx8 coloured by chain, ensemble of 10 models, front view.
PDB entry 2kx8 coloured by chain, ensemble of 10 models, side view.
PDB entry 2kx8 coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
Preformed protein-binding motifs in 7SK snRNA: structural and thermodynamic comparisons with retroviral TAR.
Durney MA, D'Souza VM
J Mol Biol 404 555-67 (2010)
PMID: 20816986

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196437 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
7SK Chain: A
Molecule details ›
Chain: A
Length: 42 nucleotides
Theoretical weight: 13.45 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand ARG 1 x ARG
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

Quick links

Citations

3 review citations

Understanding biomolecular motion, recognition, and allostery by use of conformational ensembles.
Fenwick et al. (2011)
2 more

11 mentions without citation

Progress in 7SK ribonucleoprotein structural biology.
Camara et al. (2023)
10 more