2kq7 Summary


Solution structure of the Autophagy-Related Protein Atg8

The structure was published by Schwarten, M., Stoldt, M., Mohrluder, J., and Willbold, D., in 2010 in a paper entitled "Solution structure of Atg8 reveals conformational polymorphism of the N-terminal domain" (abstract).

The structure was determined using NMR spectroscopy and deposited in 2009.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Autophagy-related protein 8. This molecule has the UniProt identifier P38182 (ATG8_YEAST)search. The sample contained 119 residues which is 100% of the natural sequence. Out of 119 residues 119 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Autophagy-related protein 8 P38182 (1-117) (ATG8_YEAST)search Saccharomyces cerevisiae S288csearch 99% 119 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P38182 (1 - 117) Autophagy-related protein 8 Saccharomyces cerevisiae

Chain Structural classification (CATH) Sequence family (Pfam)
A (P38182) Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1search PF02991: Autophagy protein Atg8 ubiquitin likesearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A (P38182) protein bindingsearch protein tagsearch ER to Golgi vesicle-mediated transportsearch protein transportsearch CVT pathwaysearch autophagic vacuole assemblysearch autophagysearch membrane fusionsearch protein targeting to vacuole involved in autophagysearch piecemeal microautophagy of nucleussearch mitochondrion degradationsearch late nucleophagysearch cellular protein complex localizationsearch transportsearch cytoplasmsearch autophagic vacuole membranesearch vacuolesearch autophagic vacuolesearch Cvt vesicle membranesearch fungal-type vacuole membranesearch pre-autophagosomal structuresearch extrinsic component of membranesearch cytoplasmic vesiclesearch membranesearch cytosolsearch vacuolar membranesearch

Chain InterPro annotation
A Autophagy protein Atg8 ubiquitin likesearch Ubiquitin-related domainsearch