2ke3 Summary


PC1/3 DCSG sorting domain in CHAPS

The structure was published by Dikeakos, J.D., Di Lello, P., Lacombe, M.J., et al., Legault, P., Reudelhuber, T.L., and Omichinski, J.G., in 2009 in a paper entitled "Functional and structural characterization of a dense core secretory granule sorting domain from the PC1/3 protease" (abstract).

The structure was determined using NMR spectroscopy and deposited in 2009.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Neuroendocrine convertase 1. This molecule has the UniProt identifier P63239 (NEC1_MOUSE)search. The sample contained 43 residues which is < 90% of the natural sequence. Out of 43 residues 43 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Neuroendocrine convertase 1 P63239 (711-753) (NEC1_MOUSE)search Mus musculussearch < 90% 43 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P63239 (711 - 753) Neuroendocrine convertase 1 Mus musculus

Chain Sequence family (Pfam)
A Prohormone convertase enzymesearch
Chain InterPro annotation
A Prohormone convertase enzymesearch