Function and Biology Details
Reaction catalysed:
Release of protein hormones, neuropeptides and renin from their precursors, generally by hydrolysis of -Lys-Arg-|- bonds.
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Neuroendocrine convertase 1 (preferred)
PDBe Complex ID:
PDB-CPX-159059 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neuroendocrine convertase 1
Molecule details ›
Chain: A
Length: 43 amino acids
Theoretical weight: 5.13 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains: Prohormone convertase enzyme
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Length: 43 amino acids
Theoretical weight: 5.13 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical:
P63239 (Residues: 711-753; Coverage: 6%)
Sequence domains: Prohormone convertase enzyme
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Refinement method:
torsion angle dynamics
Expression system: Escherichia coli
