2kbu Summary


NMR solution structure of Pin1 WW domain mutant with beta turn mimic at position 12

The structure was published by Fuller, A.A., Du, D., Liu, F., et al., Wipf, P., Gruebele, M., and Kelly, J.W., in 2009 in a paper entitled "Evaluating beta-turn mimics as beta-sheet folding nucleators." (abstract).

The structure was determined using NMR spectroscopy and deposited in 2008.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1. This molecule has the UniProt identifier Q13526 (PIN1_HUMAN)search. The sample contained 31 residues which is < 90% of the natural sequence. Out of 31 residues 31 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Q13526 (6-39) (PIN1_HUMAN)search Homo sapienssearch 97% 31 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q13526 (6 - 39) Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

Chain Sequence family (Pfam)
A (Q13526) PF00397: WW domainsearch
Chain InterPro annotation
A WW domainsearch Methyl-CpG DNA bindingsearch