› 2k40

Solution NMR

NMR structure of HESX-1 homeodomain double mutant R31L/E42L

Released:
DOI: 10.2210/pdb2k40/pdb
PDB entry 2k40 coloured by chain, ensemble of 20 models, front view.
PDB entry 2k40 coloured by chain, ensemble of 20 models, side view.
PDB entry 2k40 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Asensio J, Torrado M, Gonzalez C, Bastida A

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193687 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Homeobox expressed in ES cells 1 Chain: A
Molecule details ›
Chain: A
Length: 67 amino acids
Theoretical weight: 8.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UBX0 (Residues: 108-174; Coverage: 36%)
Gene names: HANF, HESX1
Sequence domains: Homeodomain
Structure domains: Homeodomain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

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