› 2k2t

Solution NMR

Epidermal growth Factor-like domain 2 from Toxoplasma gondii Microneme protein 6

Released:
DOI: 10.2210/pdb2k2t/pdb
PDB entry 2k2t coloured by chain, ensemble of 10 models, front view.
PDB entry 2k2t coloured by chain, ensemble of 10 models, side view.
PDB entry 2k2t coloured by chain, ensemble of 10 models, top view.
Source organism: Toxoplasma gondii
Primary publication:
Structural insights into microneme protein assembly reveal a new mode of EGF domain recognition.
Sawmynaden K, Saouros S, Friedrich N, Marchant J, Simpson P, Bleijlevens B, Blackman MJ, Soldati-Favre D, Matthews S
EMBO Rep 9 1149-55 (2008)
PMID: 18818666

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195055 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Micronemal protein 6 Chain: A
Molecule details ›
Chain: A
Length: 61 amino acids
Theoretical weight: 6.37 KDa
Source organism: Toxoplasma gondii
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9XYH7 (Residues: 87-147; Coverage: 19%)
Gene name: MIC6
Sequence domains: Human growth factor-like EGF
Structure domains: Laminin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Invasion factors are coupled to key signalling events leading to the establishment of infection in apicomplexan parasites.
Santos et al. (2011)
5 more

3 mentions without citation

Structural insights into microneme protein assembly reveal a new mode of EGF domain recognition.
Sawmynaden et al. (2008)
2 more