2k2m Summary


Structural Basis of PxxDY Motif Recognition in SH3 Binding

The structure was published by Aitio, O., Hellman, M., Kesti, T., et al., Tossavainen, H., Saksela, K., and Permi, P., in 2008 in a paper entitled "Structural basis of PxxDY motif recognition in SH3 binding." (abstract).

The structure was determined using NMR spectroscopy and deposited in 2008.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Eps8-like protein 1. This molecule has the UniProt identifier Q8TE68 (ES8L1_HUMAN)search. The sample contained 68 residues which is < 90% of the natural sequence. Out of 68 residues 68 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Eps8-like protein 1 Q8TE68 (481-536) (ES8L1_HUMAN)search Homo sapienssearch < 90% 68 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q8TE68 (481 - 536) Eps8-like protein 1 Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A SH3 Domainssearch SH3 domainsearch
Chain InterPro annotation
A SH3 domainsearch