2k0g Summary


Solution Structure of a Bacterial Cyclic Nucleotide-Activated K+ Channel Binding Domain in Complex with cAMP

The structure was published by Schunke, S., Stoldt, M., Novak, K., Kaupp, U.B., and Willbold, D., in 2009 in a paper entitled "Solution structure of the Mesorhizobium loti K1 channel cyclic nucleotide-binding domain in complex with cAMP." (abstract).

The structure was determined using NMR spectroscopy and deposited in 2008.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Mll3241 protein. This molecule has the UniProt identifier Q98GN8 (CNGK1_RHILO)search. The sample contained 142 residues which is < 90% of the natural sequence. Out of 142 residues 142 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Mll3241 protein Q98GN8 (216-355) (CNGK1_RHILO)search Mesorhizobium loti MAFF303099search 100% 142 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q98GN8 (216 - 355) Mll3241 protein Mesorhizobium loti

Chain Structural classification (CATH) Sequence family (Pfam)
A (Q98GN8) Jelly Rollssearch PF00027: Cyclic nucleotide-binding domainsearch, PF07885: Ion channelsearch

Chain ID Cellular component (GO) Molecular function (GO) Biological process (GO)
A (Q98GN8) cAMP-dependent protein kinase complexsearch cAMP-dependent protein kinase regulator activitysearch regulation of protein phosphorylationsearch

Chain InterPro annotation
A Cyclic nucleotide-binding domainsearch cAMP/cGMP-dependent protein kinasesearch RmlC-like jelly roll foldsearch Cyclic nucleotide-binding, conserved sitesearch Cyclic nucleotide-binding-likesearch