2jwa Summary

pdbe.org/2jwa
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ErbB2 transmembrane segment dimer spatial structure

The structure was published by Bocharov, E.V., Mineev, K.S., Volynsky, P.E., et al., Kirpichnikov, M.P., Efremov, R.G., and Arseniev, A.S., in 2008 in a paper entitled "Spatial Structure of the Dimeric Transmembrane Domain of the Growth Factor Receptor ErbB2 Presumably Corresponding to the Receptor Active State" (abstract).

The structure was determined using NMR spectroscopy and deposited in 2007.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Receptor tyrosine-protein kinase erbB-2.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Receptor tyrosine-protein kinase erbB-2 P04626 (641-684) (ERBB2_HUMAN)search Homo sapienssearch < 90% 44 100%
B Receptor tyrosine-protein kinase erbB-2 P04626 (641-684) (ERBB2_HUMAN)search Homo sapienssearch < 90% 44 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P04626 (641 - 684) Receptor tyrosine-protein kinase erbB-2 Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A, B Single alpha-helices involved in coiled-coils or other helix-helix interfacessearch Growth factor receptor domain IVsearch