2jvy Summary


Solution Structure of the EDA-ID-related C417F mutant of human NEMO zinc finger

The structure was published by Cordier, F., Vinolo, E., Veron, M., Delepierre, M., and Agou, F., in 2008 in a paper entitled "Solution structure of NEMO zinc finger and impact of an anhidrotic ectodermal dysplasia with immunodeficiency-related point mutation." (abstract).

The structure was determined using NMR spectroscopy and deposited in 2007.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of NF-kappa-B essential modulator. This molecule has the UniProt identifier Q9Y6K9 (NEMO_HUMAN)search. The sample contained 28 residues which is < 90% of the natural sequence. Out of 28 residues 28 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A NF-kappa-B essential modulator Q9Y6K9 (394-419) (NEMO_HUMAN)search Homo sapienssearch < 90% 28 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q9Y6K9 (394 - 419) NF-kappa-B essential modulator