2jv1 Summary

pdbe.org/2jv1
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NMR structure of human insulin monomer in 35% CD3CN zinc free, 50 structures

The structure was published by Bocian, W., Sitkowski, J., Bednarek, E., Tarnowska, A., Kawecki, R., and Kozerski, L., in 2008 in a paper entitled "Structure of human insulin monomer in water/acetonitrile solution." (abstract).

The structure was determined using NMR spectroscopy and deposited in 2007.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Insulin.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Insulin P01308 (90-110) (INS_HUMAN)search Homo sapienssearch 100% 21 100%
B Insulin P01308 (25-54) (INS_HUMAN)search Homo sapienssearch 100% 30 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P01308 (90 - 110) Insulin Homo sapiens

Chain Structural classification (SCOP) Sequence family (Pfam)
A (P01308) PF00049: Insulin/IGF/Relaxin familysearch
B (P01308) Isolated insulin B-chainsearch PF00049: Insulin/IGF/Relaxin familysearch

Chain ID Cellular component (GO) Molecular function (GO)
A (P01308) extracellular regionsearch hormone activitysearch
B (P01308) extracellular regionsearch hormone activitysearch

Chain InterPro annotation
A Insulin-likesearch Insulin, conserved sitesearch
B Insulinsearch Insulin-likesearch