2juu Summary

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allo-ThrA3 DKP-insulin

The structure was published by Huang, K., Chan, S.J., Hua, Q.X., et al., Steiner, D.F., Katsoyannis, P.G., and Weiss, M.A., in 2007 in a paper entitled "The A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor: PHOTO-CROSS-LINKING AND MUTAGENESIS OF A DIABETES-RELATED CREVICE." (abstract).

The structure was determined using NMR spectroscopy and deposited in 2007.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Insulin A chain and Insulin B chain.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Insulin A chain P01308 (90-110) (INS_HUMAN)search Homo sapienssearch 100% 21 100%
B Insulin B chain P01308 (25-54) (INS_HUMAN)search Homo sapienssearch 100% 30 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P01308 (90 - 110) Insulin A chain

Chain Structural classification (SCOP) Sequence family (Pfam)
A (P01308) PF00049: Insulin/IGF/Relaxin familysearch
B (P01308) Isolated insulin B-chainsearch PF00049: Insulin/IGF/Relaxin familysearch
Chain InterPro annotation
A Insulin-likesearch Insulin, conserved sitesearch
B Insulin-likesearch